Alternative Description: Lamin B
Catalogue Number: IQ176
Also known as: LAMB2; Lamin B1; Lamin B2; LMN2; LMN; LMNB; LMNB1; LMNB2; MGC111419; MGC2721;
Quantity: 2ml
Price: £219.00Price excludes VAT and Delivery.
Clone: X223;
Host/Isotype: Mouse IgG1;
Immunogen: Nuclear pore complex-lamina fraction of Xenopus laevis (XLKE-A6 cells)
Specificity: This antibody decorates the karyoskeleton, i.e. the intermediate filament equivalent of the nucleus. Reacts with lamin isotypes of Mr 60 -75 kD. Recognises Lamin B1 & B2 in human, bovine & rat, and Lamin B2 in mouse
Purification: Unpurified;
Format: Tissue culture supernatant containing 0.09% sodium azide;
Applications: IF; WB;
View Applications KeyDilutions: Optimal antibody dilution should be determined by titration. Ready to use for immunohistochemistry, and up to 1/50 for western blot (ECL technique)
References: (click to view full details)
The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology - Sebastian Ulbert et al ( FEBS Letters,3 November 2006)
The nuclear lamins. A multigene family of proteins in evolution and differentiation.- Krohne G ( Exp Cell Res.,Jan 1986)
Research areas: Apoptosis; Cell Biology; Class V Lamins; Cytoskeleton; Cytoskeleton / ECM; Intermediate Filaments; Lamins; Nuclear Envelope; Nucleus; Subcellular Markers; Tags & Cell Markers;
Storage: Store at +4°C for one month, or in small aliquots at -20°C for longer
Health and safety: Products that contain sodium azide (a poisonous and hazardous substance) should be handled only by trained personnel
Entrez Gene ID: Rat;
Omim ID: 150340 (Human);
Protocols: Immunofluorescence protocol - Formaldehyde fixation; Immunofluorescence protocol - Methanol/acetone fixation; Western Blotting Protocol;
