PDE1A Antibody- Rabbit Anti- Phosphodiesterase 1A
Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3 5-monophosphate (cAMP and cGMP) Thus these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling PDE1 has three subtypes PDE1A PDE1B and PDE1C PDE1A and PDE1B have higher affinity for cGMP than for cAMP whereas PDE1C has high affinity for both cAMP and cGMP