Checkpoint Control Antibodies Ageing

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Mad1L1 Antibody- Mouse Anti-Mad1L1

MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate MAD1L1 functions as a homodimer and interacts with MAD2L1 MAD1L1 may play a role in cell cycle control and tumor suppression

£183.00

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MCPH1 (BRIT1) Antibody- Mouse Anti-MCPH1 (BRIT1)

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome MCPH1 looks like it might be a useful prognostic indicator in breast cancer associated with BRCA1 inactivation

£226.00

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