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TRF1 Antibody- Mouse Anti-TRF1
The TRF1 gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex It is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase acting in cis to limit the elongation of individual chromosome ends The protein structure contains a C-terminal Myb motif a dimerization domain near its N-terminus and an acidic N-terminus Two transcripts of this gene are alternatively spliced products
Y14 Antibody- Mouse Anti-Y14
Y14 is a protein with a conserved RNA-binding motif It is preferentially associated with mRNAs produced by splicing including both nuclear mRNAs and newly exported cytoplasmic mRNAs It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present thus coupling pre- and post-mRNA splicing events Previously it was thought that two genes encode this protein RBM8A and RBM8B it is now thought that the RBM8B locus is a pseudogene Two alternative start codons result in two forms of the protein and this gene also uses multiple polyadenylation sites
