Ageing DNA Damage Repair

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MCPH1 (BRIT1) Antibody- Mouse Anti-MCPH1 (BRIT1)

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome MCPH1 looks like it might be a useful prognostic indicator in breast cancer associated with BRCA1 inactivation

£226.00

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Mus81 Antibody- Mouse Anti-Mus81

Reduction or loss of a protein called Mus81 can led to the development of lymphomas and other tumours in mice Mus81 is a protein long thought to be involved in repairing DNA that is damaged during normal metabolic processes

£183.00

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