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Ageing Neurodegeneration

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NQO1 Antibody- Mouse Anti-NAD(P)H:quinone oxidoreductase 1
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase This FAD-binding protein forms homodimers and reduces quinones to hydroquinones This proteins enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species Mutations in this gene have been associated with tardive dyskinesia (TD) an increased risk of hematotoxicity after exposure to benzene and susceptibility to various forms of cancer Altered expression of this protein has been seen in many tumors and is also associated with Alzheimers disease (AD) Alternate transcriptional splice variants encoding different isoforms have been characterized
£226.00

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NQO1 Antibody- Mouse Anti-NAD(P)H:quinone oxidoreductase 1
This gene (NQO1) is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase This FAD-binding protein forms homodimers and reduces quinones to hydroquinones This proteins enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species Mutations in this gene have been associated with tardive dyskinesia (TD) an increased risk of hematotoxicity after exposure to benzene and susceptibility to various forms of cancer Altered expression of this protein has been seen in many tumors and is also associated with Alzheimers disease (AD) Alternate transcriptional splice variants encoding different isoforms have been characterized
£183.00

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PDE10A Antibody- Rabbit Anti- Phosphodiesterase 10A
Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3 5-monophosphate (cAMP and cGMP) Thus these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling The PDE10 enzyme belongs to a family of PDEs that hydrolyse both cAMP and cGMP
£226.00

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