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hnRNP-C1/C2 Antibody- Mouse Anti-hnRNP-C1/C2
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm The hnRNP proteins have distinct nucleic acid binding properties hnRNP C1 and C2 are encoded by one gene the two alternatively spliced transcript variants have been described
£226.00
hnRNP-C1/C2 Antibody- Mouse Anti-hnRNP-C1/C2
The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm The hnRNP proteins have distinct nucleic acid binding properties hnRNP C1 and C2 are encoded by one gene the two alternatively spliced transcript variants have been described
£183.00
Lamin A/C - Mouse Anti-Lamin A/C
Nuclear Lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane Two main subtypes of nuclear lamins can be distinguished ie A-type Lamins and B-type Lamins The A-type Lamins comprise a set of three proteins arising from the same gene by alternative splicing ie Lamin A Lamin C and Lamin Adel 10 while the B-type Lamins include two proteins arising from two distinct genes ie Lamin B1 and Lamin B2 Recent evidence has revealed that mutations in A-type Lamins give rise to a range of rare but dominant genetic disorders including Emery-Dreifuss muscular dystrophy dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy In addition the expression of A-type Lamins coincides with cell differentiation and as A-type Lamins specifically interact with chromatin a role in the regulation of differential gene expression has been suggested for A-type Lamins
£183.00
NQO1 Antibody- Mouse Anti-NAD(P)H:quinone oxidoreductase 1
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase This FAD-binding protein forms homodimers and reduces quinones to hydroquinones This proteins enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species Mutations in this gene have been associated with tardive dyskinesia (TD) an increased risk of hematotoxicity after exposure to benzene and susceptibility to various forms of cancer Altered expression of this protein has been seen in many tumors and is also associated with Alzheimers disease (AD) Alternate transcriptional splice variants encoding different isoforms have been characterized
£226.00
NQO1 Antibody- Mouse Anti-NAD(P)H:quinone oxidoreductase 1
This gene (NQO1) is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase This FAD-binding protein forms homodimers and reduces quinones to hydroquinones This proteins enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species Mutations in this gene have been associated with tardive dyskinesia (TD) an increased risk of hematotoxicity after exposure to benzene and susceptibility to various forms of cancer Altered expression of this protein has been seen in many tumors and is also associated with Alzheimers disease (AD) Alternate transcriptional splice variants encoding different isoforms have been characterized
£183.00
