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Ageing Tumor Supressors

Tumor suppressors play important roles in the regulation mechanisms of tissue homeostasis, cell self-renewal, regeneration, and aging.

Cell division and reproduction can be negatively impacted by stressors internal and external resulting in cellular senescence , ageing and disease.

In cellular senescence, the mechanism is managed by p53 and RB tumor suppressor proteins and is an important anticancer mechanism. Senescent cells may undergo changes that contribute to aging and certain age-related diseases, including late onset cancers. The senescence response maybe promoting early-life survival by restraining the potential of child hood disease and cancers but eventually limiting life span as senescent cells accumulate gradually over time .

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Western blot - Lamin A + C antibody [JoL5] - Nuclear Envelope Marker
Primary Description:

Mouse Anti-Lamin A + C antibody [JoL5] - Nuclear Envelope Marker

Product Reference Code: IQ252
Species Reactivity:

Mouse, Human

Applications:

ICC/IF, WB

£183.00

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Immunostaining reaction of lamin A antibody with human epidermis
Primary Description:

Mouse Anti-Lamin A [133A2]

Product Reference Code: IQ248
Species Reactivity:

Mouse, Rat, Cow, Dog, Human, Monkey

Applications:

Flow Cyt, IHC-Fr, WB, IHC-P, ICC/IF, IP

£183.00

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Lamin expression in basal cell skin carcinomas. Frozen sections stained with Lamin A antibody [JOL4]
Primary Description:

Mouse Anti-Lamin A [JOL4]

Product Reference Code: IQ330
Species Reactivity:

Human, Mouse

Applications:

IF, IHC(Fr), IP, WB

£183.00

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Immunohistochemistry of Anti-Lamin A+C on formalin fixed paraffin embedded skin tissue
Primary Description:

Mouse Anti-Lamin A+C [JOL2]

Product Reference Code: IQ332
Species Reactivity:

Human, African Green Monkey

Applications:

ICC/IF, IHC-Fr, IHC-P, WB, IP, Flow Cyt

£199.00

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Immunocytochemistry/ Immunofluorescence - Lamin A + C antibody [JoL3] - Nuclear Envelope Marker
Primary Description:

Mouse Anti-Lamin A + C antibody [JoL3] - Nuclear Envelope Marker

Product Reference Code: IQ251
Species Reactivity:

Mouse, Rat, Human

Applications:

WB, ICC/IF

£183.00

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Immunohistochemistry showing Lamin C on formalin fixed paraffin embedded skin tissue at 1:100
Primary Description:

Rabbit Anti-Lamin C

Product Reference Code: IQ177
Species Reactivity:

Human, Mouse, Rat 

Applications:

ICC/IF, IHC-P, IHC-Fr, WB, Flow

£226.00

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Primary Description:

Rabbit Anti-LAP2 alpha

Product Reference Code: IQ175
Species Reactivity:

Mouse, Rat, Human

Applications:

ChIP, IP, ICC/IF, WB

£226.00

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Western blot - Anti-MAD1 antibody [9B10]
Primary Description:

Mouse Anti-Mad1 [9B10]

Product Reference Code: IQ200
Species Reactivity:

Human 

Applications:

IP, ICC/IF, Flow Cyt

£226.00

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Western blot - Anti-MAD1 antibody [9B10]
Primary Description:

Mouse Anti-Mad1 [9B10]

Product Reference Code: IQ253
Species Reactivity:

Human 

Applications:

IP, ICC/IF, Flow Cyt

£183.00

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Primary Description:

Rabbit Anti-OVCA1

Product Reference Code: IQ325
Species Reactivity:

Human

Applications:

WB

£226.00

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Primary Description:

Rabbit Anti-OVCA1

Product Reference Code: IQ326
Species Reactivity:

Human

Applications:

WB

£183.00

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