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BUB1 Antibody - Mouse (monoclonal) Anti-BUB1 0.1ml
Bub1 is a kinase involved in spindle checkpoint function The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint Mutations in Bub1 have been associated with aneuploidy and several forms of cancer
BUB1 Antibody - Mouse Anti-BUB1 50ul
Bub1 is a kinase involved in spindle checkpoint function The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint Mutations in Bub1 have been associated with aneuploidy and several forms of cancer
MCPH1 (BRIT1) Antibody- Mouse Anti-MCPH1 (BRIT1)
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome
MCPH1 looks like it might be a useful prognostic indicator in breast cancer associated with BRCA1 inactivation
