Angiogenesis is the growth of new blood vessels from preexisting blood vessels. Whilst this process is normally positive (e.g in embryo maturation) it is a key requirement in the etiology of cancer and tumour formation and growth.
Angiogenesis in this case is the proliferation of a network of blood vessels that penetrates into cancerous areas. In its so called sprouting form the new vessels emerge stimulated by angiogenic growth factors, via endothelial cell proliferation. Whereas in other forms the core vessel split to form a new network.
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Nestin Antibody- Mouse Anti-Nestin
Nestin is a Class VI intermediate filament expressed in the developing central nervous system (CNS) in early embryonic neuroepithelial stem cells This protein has been widely used as a predominant marker for stem / progenitor cells glioma cells and tumor endothelial cells in the mammalian CNS Furthermore it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumor This highly specific antibody to human nestin can aid in characterizing progenitor cells differentiating into distinct lineages in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury and in identifying neuroepithelial tumor cells
£183.00
