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Cancer Metabolism

Scientists have been researching cell metabolism for some decades and this is an important topic in cancer, as cancer cells seem to use energy differently from normal cells.

The study of cancer metabolism started in the 1940s, when Otto Warburg found that rapidly dividing cancer cells didn’t consume oxygen in the same way as rapidly dividing normal cells.

Nearly 10 years ago, the scientific establishment believed cancer was caused by a dysfunction of metabolism, but the idea soon became unpopular. Now, scientists are again looking at metabolism and its role in cancer and other common diseases. Metabolism is a connected network of reactions that are arranged in parallel and interact with each other in different pathways. Such parallelism can mask how genes are linked with disease traits and make it difficult to treat conditions.

Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells.

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FFPE of Human pituitary gland using Anti-ACTH N-Terminal, clone 6Y8
Primary Description:

Mouse Anti-ACTH N-Terminal Antibody 6Y8 [57]

Product Reference Code: IQ427
Species Reactivity:

Human

Applications:

IHC(P)

£226.00

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Primary Description:

Mouse Anti-ACTH N-Terminal Antibody 6Y8 [57]: Horseradish Peroxidase (HRP)

Product Reference Code: IQ427HRP
Species Reactivity:

Human

Applications:

IHC-P

£245.00

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Primary Description:

Mouse Anti-Apolipoprotein E4 [4E4]

Product Reference Code: IQ552
Species Reactivity:

Human

Applications:

Dot blot, ELISA, WB, IP, flow cytometry

£226.00

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Immunohistochemistry of Aurora B antibody on formalin fixed paraffin embedded skin tissue
Primary Description:

Sheep Anti-Aurora B

Product Reference Code: IQ234
Species Reactivity:

Human 

Applications:

WB, IHC(P)

£226.00

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Ovarian cancer cells were arrested with Nocodazole before fixation; primary Ab: anti-Bub1 mAb (clone 14H5); Secondary Ab: anti-mouse Alexa 488; chromosome visualization: DAPI
Primary Description:

Mouse Anti-Bub1 [14H5]

Product Reference Code: IQ198
Species Reactivity:

Mouse, Human. Predicted to work with: Rat, Xenopus laevis, Kangaroo

Applications:

Flow Cyt, ICC/IF, WB, IHC-P

£226.00

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Ovarian cancer cells were arrested with Nocodazole before fixation; primary Ab: anti-Bub1 mAb (clone 14H5); Secondary Ab: anti-mouse Alexa 488; chromosome visualization: DAPI
Primary Description:

Mouse Anti-Bub1 [14H5]

Product Reference Code: IQ255
Species Reactivity:

Mouse, Human. Predicted to work with: Rat, Xenopus laevis, Kangaroo

Applications:

Flow Cyt, ICC/IF, WB, IHC-P

£183.00

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Western blot analysis of Cytochrome b245 Light Chain Antibody [44.1] expression in human spleen
Primary Description:

Mouse Anti-Cytochrome b245 Light Chain [44.1]

Product Reference Code: IQ436
Species Reactivity:

Human

Applications:

WB

£226.00

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Western blot analysis of Cytochrome b245 Light Chain Antibody [CS9] expression in human spleen
Primary Description:

Mouse Anti-Cytochrome b245 Light Chain [CS9]

Product Reference Code: IQ434
Species Reactivity:

Human 

Applications:

WB, IP, IHC-Fr, Flow Cyt, Indirect ELISA

£226.00

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Immunohistochemistry of Anti-Cytokeratin 13 [AE8] on formalin fixed paraffin embedded tonsil tissue
Primary Description:

Mouse Anti-Cytokeratin 13 [AE8]

Product Reference Code: IQ291
Species Reactivity:

Mouse, Rabbit, Human

Applications:

WB, IHC-P

£226.00

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Frozen section of Mouse thymus stained with Anti-EpCAM, clone G8.8
Primary Description:

Rat Anti-EpCAM [G8.8]

Product Reference Code: IQ446
Species Reactivity:

Mouse

Applications:

IHC-Fr, IP, WB

£226.00

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Primary Description:

Rabbit Anti-FNIP1

Product Reference Code: IQ351
Species Reactivity:

Mouse, Human

Applications:

WB, IP

£226.00

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Primary Description:

Mouse anti-HCG BETA [WM16/71]

Product Reference Code: IQ371
Species Reactivity:

Human

Applications:

ELISA, RIA

£226.00

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Primary Description:

Mouse Anti-HDAC3 [3G6]

Product Reference Code: IQ553
Species Reactivity:

Human, Mouse 

Applications:

WB , IP , ICC/IF

£226.00

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Primary Description:

Mouse Anti-HIF-2 alpha 

Product Reference Code: IQ601
Species Reactivity:

Human

Applications:

ELISA, IHC-Fr, IHC-P, WB

£226.00

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Staining of paraffin lung tissue sections showing squamous cell carcinoma, using hnRNP A2B1 antibody
Primary Description:

Mouse Anti-hnRNP A2B1 [DP3B3]

Product Reference Code: IQ215
Species Reactivity:

Chicken, Human, Mouse, Rat, Pig 

Applications:

ICC/IF, IHC-Fr, ELISA, WB, IP, IHC-P

£226.00

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Staining of paraffin lung tissue sections showing squamous cell carcinoma, using hnRNP A2B1 antibody
Primary Description:

Mouse Anti-hnRNP A2B1 [DP3B3]

Product Reference Code: IQ271
Species Reactivity:

Chicken, Human, Mouse, Rat, Pig

Applications:

ICC/IF, IHC-Fr, ELISA, WB, IP, IHC-P

£183.00

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