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M Cancer

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Mad1L1 Antibody- Mouse Anti- Mad1L1
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate MAD1L1 functions as a homodimer and interacts with MAD2L1 MAD1L1 may play a role in cell cycle control and tumor suppression
£226.00

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Mad1L1 Antibody- Mouse Anti-Mad1L1
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate MAD1L1 functions as a homodimer and interacts with MAD2L1 MAD1L1 may play a role in cell cycle control and tumor suppression
£183.00

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MERTK Antibody- Mouse Anti-Mer Receptor Tyrosine Kinase
In vertebrates the photoreceptor cells are the basic sensory apparatus of the retina primarily converting photon energy absorbed from light into neuronal signals The photoreceptor proximal outer segments are synthesized daily by cell bodies and outer segment tips are removed with a circadian rhythm The shed outer segments are endocytosed by adjacent retinal pigment epithelial (RPE) cells and are recycled to photoreceptors The receptor tyrosine kinase MERTK protein is an approximately 120-122 kDa (994 amino acids) protein expressed in RPEs MERTK has a tyrosine kinase domain close to the C-terminal region and putative phosphorylation sites Mutation of MERTK in the Royal College of Surgeons (RCS) rat results in defective phagocytosis of photoreceptor outer segments by the retinal pigment epithelium (RPE) and retinal degeneration resulting in retinitis pigmentosa
£226.00

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Mus81 Antibody- Mouse Anti-Mus81
Reduction or loss of a protein called Mus81 can led to the development of lymphomas and other tumours in mice Mus81 is a protein long thought to be involved in repairing DNA that is damaged during normal metabolic processes
£183.00

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