Transportin1 (TRN) Antibody- Mouse Anti-Transportin1
Heterogeneous nuclear ribonucleoprotein hnRNPA1 is an abundant nuclear protein that plays an important role in pre-mRNA processing and mRNA export from the nucleus A1 shuttles rapidly between the nucleus and the cytoplasm and a 38-amino acid domain M9 serves as the bi-directional transport signal of A1 Recently a 90-kD protein transportin was identified as the mediator of A1 nuclear import Transportin mediates the nuclear import of additional hnRNP proteins including hnRNPF The nuclear localization of A1 is dependent on ongoing RNA polymerase II transcription