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Transcription Factor Antibodies Cancer

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EAPP Antibody ; Mouse Anti-EAPP
Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis
£226.00

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Mus81 Antibody- Mouse Anti-Mus81
Reduction or loss of a protein called Mus81 can led to the development of lymphomas and other tumours in mice Mus81 is a protein long thought to be involved in repairing DNA that is damaged during normal metabolic processes
£183.00

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