My Account My Wishlist

• Home
• Antibody Categories

  Cell Adhesion Marker Antibodies Cell Cycle Antibodies Cell Signalling Antibodies Checkpoint Control Antibodies Chemokine Receptor Antibodies Cytoskeleton Antibodies Disease Related Antibodies DNA Damage Recognition Antibodies Growth Factor Antibodies Hormone & Receptor Antibodies Immunology Antibodies Metabolism Antibodies Microbiology Antibodies Neuroscience Antibodies Nuclear Envelope Antibodies Nuclear Pore Complex Antibodies Nuclear Transport Antibodies Phosphorylated Antibodies Phototransduction Antibodies Rna Binding Protein Antibodies Tag Antibodies T Cell Receptor Antibodies Transcription Factor Antibodies Viral Transcription Antibodies

• Research Areas

  Ageing » Stress Proteins Apoptosis Chromatin DNA Damage Repair Lamins Neurodegeneration Telomeres Tumor Suppressors Cancer » Angiogenic Factors Apoptosis Co-activators/co-repressors DNA Synthesis Growth Factors Hormones their receptors HIV Lamins Oncoproteins Proto-oncogenes Ras Family Telomeres Tumor Suppressors Cancer Metabolism Cell Biology » Post-transitional modifications Metabolic Enzymes Metabolism Apoptosis Cell Movement Cell Proliferation Centromere Centrosomes Chromatin Cytoskeleton Growth Factors Intermediate Filaments Kallikreins Lamins mRNA processing Nuclear Envelope Nuclear Import / Export Oncoproteins P bodies/GW bodies Receptor Proteins RNA Processing Steroid hormone receptor activity Cell Division » Centromere Centrosomes Checkpoint Proteins DNA Synthesis Lamins Oncoproteins signal transduction Telomeres Tumor Suppressors Cell Architecture » Actin Cytoskeleton Cell Adhesion Molecules Centromere Centrosomes Cytoskeleton Extra Cellular Matrix Proteins Intermediate Filaments Lamins Nuclear Envelope Microtubule Cytoskeleton Development » Acetylation Apoptosis Chromatin Co-activators/co-repressors Cytokeratins Growth Factors HLH / Leucine Zipper Hormones their receptors Lamins Oncoproteins Germ Cell Markers Epigenetics » Acetylation Chromatin Lamins Nuclear Envelope Human Disease » Inherited Degenerative Disorders Cognitive/Mental Disorders Infectious Diseases Immune Deficiency Immunology » B-cell Markers HIV Influenza T-cell Markers Inherited Diseases » Cytokeratins Intermediate Filaments Lamins Neurodegeneration Nuclear Envelope Oncoproteins Tumor Suppressors Microbiology » Calcium ion binding HIV Influenza Metal ion binding Toxin Nuclear Signalling » Apoptosis Chromatin Lamins Nuclear Envelope Nuclear Import / Export Nuclear Pores Nucleoplasm RNA Processing Spliceosomes Telomeres Neuroscience » Metabolism Visual System Neurodegeneration Neuronal Markers Neuron Parkinsons Disease Signal Transduction » Stress Pathways Acetylation Cell Division Co-activators/co-repressors Growth Factors HLH / Leucine Zipper Hormones their receptors Lamins Lipid binding Protein Phosphorylation Proto-oncogenes Ras Family Receptor Proteins Steroid hormone receptor activity Transmembrane Telomeres Tumor Suppressors Sub Cellular markers » Chromatin Cytokeratins Golgi Apparatus Intermediate Filaments Lamins Lysosomes Nuclear Envelope Plasma Membranes Stem Cells » CD Antigens Transcription » Acetylation Chromatin Co-activators/co-repressors HLH / Leucine Zipper mRNA processing Oncoproteins RNA Processing RNA Synthesis Splicing

• New Antibodies
• Services

  Antibody Licensing Research Customer Service Protocols Custom Antibody Services Our Antibodies Quality Antibodies

• About
• Support
• Distributors
• OEM Customers
• Contact

A centrosome is a specialised cellular sub unit or organelle that acts as the main microtubule organising structure in the cell. Centrosomes are implicated in the accuracy and efficacy of cellular division and cell cycle progression.

Centrosomes can be altered in cancer cells with both structural and numeric aberrations. With structural aberrations the centrosome variations appear too large, due to uncontrolled expression of certain core components and this type of enlargement can often been seen in tumours. Numeric aberrations, excessive or even supernumerary are generated by reduplication or cell division failures.