Cell Architecture Microtubule Cytoskeleton
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CENP-E Antibody - Mouse Anti-CENP-E 0.1ml
CENPE is a 250-300 kDa human centromere-associated kinesin-like motor protein that accumulates in G2 phase In contrast to other centromere proteins CENPE is not detected at centromeres during interphase and first appears at the centromere region of chromosomes during prometaphase CENPE function is required for the transition from metaphase to anaphase CENPE is probably one of the motors responsible for mammalian chromosome movement and/or spindle elongation
£226.00
CENP-E Antibody - Mouse Anti-CENP-E 50ul
CENPE is a 250-300 kDa human centromere-associated kinesin-like motor protein that accumulates in G2 phase In contrast to other centromere proteins CENPE is not detected at centromeres during interphase and first appears at the centromere region of chromosomes during prometaphase CENPE function is required for the transition from metaphase to anaphase CENPE is probably one of the motors responsible for mammalian chromosome movement and/or spindle elongation
£183.00
Mad1p Antibody- Rabbit Anti-Mad1p
MAD1 is a non-essential gene that encodes a component of the spindle checkpoint. The spindle checkpoint delays the onset of anaphase in cells with defects in mitotic spindle assembly or in the attachment of chromosomes to the spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization
£226.00
Mad2L1 Antibody- Mouse Anti-Mad2L1
Mad2L1 is required for the execution of the mitotic checkpoint which monitors the process of kinetochore spindle attachment and delays the onset of anaphase when this process is not complete It inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate
£226.00
Mad2p Antibody- Rabbit Anti-Mad2p
MAD2 is a non-essential gene that encodes a component of the spindle checkpoint. The spindle checkpoint delays the onset of anaphase in cells with defects in mitotic spindle assembly or in the attachment of chromosomes to the spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators.hMAD2 is the human homologue of yeast MAD2
£226.00
