Oncoproteins are produced from oncogenic gene expression as result of mutation of a normal gene into an onco gene, one which may have the potential to cause cancer.
Proto oncogenes are normal ones which carry the potential to be cancer forming ones, and can be triggered through mutagenic processes, cell growth misregulation or an abnormal translocation of a chromosome.
New research indicates that antibodies can target intracelluar oncoproteins. Most recently it was thought that oncoproteins like PRL-3 could not be accessed via antibody attack as antibodies were too big to relocate them selves into the cell via the cell membrane.
| Primary Description: | Mouse Anti-MERTK [A311F9G3] |
| Product Reference Code: | IQ340 |
| Species Reactivity: | Human |
| Applications: | WB |
| Primary Description: | Rabbit Anti-OVCA1 |
| Product Reference Code: | IQ325 |
| Species Reactivity: | Recognises human OVCA1 endogenous protein on A2780 whole cell lysate OVCAR5 total protein extract ; |
| Applications: | WB; |
| Primary Description: | Rabbit Anti-OVCA1 |
| Product Reference Code: | IQ326 |
| Species Reactivity: | Recognises human OVCA1 endogenous protein on A2780 whole cell lysate OVCAR5 total protein extract ; |
| Applications: | WB; |
| Primary Description: | Rabbit Anti-OVCA2 |
| Product Reference Code: | IQ327 |
| Species Reactivity: | Recognises human OVCA2 endogenous protein on A2780 SKOV3 extract ; |
| Applications: | WB; |