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Cell Division Checkpoint Proteins

Checkpoint proteins play a key element in the regulation of the cell cycle. Checkpoints are made up of composites of protein kinases and adaptor proteins that are relevant for the integrity of the cell division process.

Examples are p53 that plays a role in halting the cell cycle in the G1 and has role in cell apoptosis. The ATM protein is involved in detecting double strand breaks in DNA and MAD can block entry to anaphase in cell division.

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immunofluorescence image showing COS cells stained with BRIT1 Antibody [AB11] expressing GFP microcephalin
Primary Description:

Mouse Anti-BRIT1 [AB11]

Product Reference Code: IQ539
Species Reactivity:

Human

Applications:

WB, ICC/IF, ELISA, IP

£226.00

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Ovarian cancer cells were arrested with Nocodazole before fixation; primary Ab: anti-Bub1 mAb (clone 14H5); Secondary Ab: anti-mouse Alexa 488; chromosome visualization: DAPI
Primary Description:

Mouse Anti-Bub1 [14H5]

Product Reference Code: IQ198
Species Reactivity:

Mouse, Human. Predicted to work with: Rat, Xenopus laevis, Kangaroo

Applications:

Flow Cyt, ICC/IF, WB, IHC-P

£226.00

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Ovarian cancer cells were arrested with Nocodazole before fixation; primary Ab: anti-Bub1 mAb (clone 14H5); Secondary Ab: anti-mouse Alexa 488; chromosome visualization: DAPI
Primary Description:

Mouse Anti-Bub1 [14H5]

Product Reference Code: IQ255
Species Reactivity:

Mouse, Human. Predicted to work with: Rat, Xenopus laevis, Kangaroo

Applications:

Flow Cyt, ICC/IF, WB, IHC-P

£183.00

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Ovarian cancer cells were arrested with Nocodazole before fixation; primary Ab: anti-CenpE mAb (clone 1H12); Secondary Ab: anti-mouse Alexa 488; chromosome visualization: DAPI
Primary Description:

Mouse Anti-CENPE [1H12]

Product Reference Code: IQ201
Species Reactivity:

Human 

Applications:

ICC/IF, IP, ICC, WB, Flow Cyt

£226.00

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Ovarian cancer cells were arrested with Nocodazole before fixation; primary Ab: anti-CenpE mAb (clone 1H12); Secondary Ab: anti-mouse Alexa 488; chromosome visualization: DAPI
Primary Description:

Mouse Anti-CENPE [1H12]

Product Reference Code: IQ254
Species Reactivity:

Human 

Applications:

ICC/IF, IP, ICC, WB, Flow Cyt

£183.00

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Primary Description:

Rabbit Anti-Mad1

Product Reference Code: IQ242
Species Reactivity:

Saccharomyces cerevisiae

Applications:

WB, ICC/IF

£226.00

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Primary Description:

Rabbit Anti-Mad2

Product Reference Code: IQ243
Species Reactivity:

Human, Saccharomyces cerevisiae

Applications:

WB, ICC/IF

£226.00

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Colon cancer fixed with formalin (after antigen retreival) and stained with Mad2L1 antibody, clone 17D10
Primary Description:

Mouse Anti-Mad2L1 [17D10]

Product Reference Code: IQ239
Species Reactivity:

Human

Applications:

IHC(P), IP, WB

£226.00

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Western blot - Mus81 antibody [mta30 2g10/3]
Primary Description:

Mouse Anti-Mus81 [MTA30 2G10/3]

Product Reference Code: IQ285
Species Reactivity:

Human 

Applications:

WB, IP, ICC/IF, Flow Cyt

£183.00

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Primary Description:

Sheep Anti-NEK2

Product Reference Code: IQ231
Species Reactivity:

Recognises both splice variants of human NEK2 (NEK2A and NEK2B)

Applications:

WB

£226.00

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Primary Description:

Rat Anti-ORC3L [1D6]

Product Reference Code: IQ308
Species Reactivity:

Human 

Applications:

IP, WB

£183.00

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