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MCPH1 (BRIT1) Antibody- Mouse Anti-MCPH1 (BRIT1)
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome
MCPH1 looks like it might be a useful prognostic indicator in breast cancer associated with BRCA1 inactivation
£226.00
Receptor Tyrosine Phosphatase Beta (phosphacan) Antibody- Mouse Anti-Receptor Tyrosine Phosphatase Beta (phosphacan)
PTPRB is a member of the protein tyrosine phosphatase (PTP) family The family comprises at least 37 proteins characterized by a catalytic phosphatase domain of approximately 240 amino acids and includes both transmembrane and cytosolic enzymes PTP1B is a transmembrane PTP The PTPs have high substrate specificity for phosphotyrosyl proteins at the primary sequence level sharing little similarity with the protein serine phosphatases protein threonine phosphatases or the acid and alkaline phosphatases PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins which are critical in physiological and pathological events such as cell migration adhesion and transformation
£183.00
Receptor Tyrosine Phosphatase Beta (phosphacan) Antibody- Mouse Anti-Receptor Tyrosine Phosphatase Beta (phosphacan)
PTPRB is a member of the protein tyrosine phosphatase (PTP) family The family comprises at least 37 proteins characterized by a catalytic phosphatase domain of approximately 240 amino acids and includes both transmembrane and cytosolic enzymes PTP1B is a transmembrane PTP The PTPs have high substrate specificity for phosphotyrosyl proteins at the primary sequence level sharing little similarity with the protein serine phosphatases protein threonine phosphatases or the acid and alkaline phosphatases PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins which are critical in physiological and pathological events such as cell migration adhesion and transformation
£226.00
