Signal transduction is an extracellular mechanism that stimulates an intracellular activity or response. In more complex signalling the process involves binding signalling molecules and ligands to cell surface receptors that trigger cellular events via ionic flow into and out of the cell.
For simple signalling ionic flow results in changes in the electrical potential of the cell, promotes signal propagation and here signals can be instigated by a variety of inputs e.g. photonic impacts on the retina.
| Primary Description: | Rabbit Anti-APPL1 |
| Product Reference Code: | IQ350 |
| Species Reactivity: | Mouse, Rat, Human |
| Applications: | IP, WB, ICC/IF, IHC-P |
| Primary Description: | Mouse Anti-Histone H4 (mono methyl K20) [5E10-D8] |
| Product Reference Code: | IQ551 |
| Species Reactivity: | Human. Predicted to work with: Xenopus laevis, Arabidopsis thaliana, Fruit fly (Drosophila melanogaster), all Mammals |
| Applications: | Dot blot, WB against endogenous protein, ELISA, ChIP |
| Primary Description: | Mouse Anti-Insulin-Like Growth Factor [7973] |
| Product Reference Code: | IQ391 |
| Species Reactivity: | Human, Mouse, Rat |
| Applications: | RIA, ELISA, IHC(Fr), IHC(P) |
| Primary Description: | Mouse Anti-Parathyroid Hormone Receptor 1 [3D1.1] |
| Product Reference Code: | IQ393 |
| Species Reactivity: | 3D1.1 reacts with the human Type I hPTH/PTHrP and it does not react with the Type II receptor |
| Applications: | EIA, FACS, IB, IHC (paraffin sections); |
| Primary Description: | Rabbit Anti-PDE10A |
| Product Reference Code: | IQ357 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to the PDE10A enzyme, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE11A |
| Product Reference Code: | IQ356 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to members of the PDE11A sub-family, in human, mouse, rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE1A |
| Product Reference Code: | IQ367 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to the PDE1A sub-family, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE2A |
| Product Reference Code: | IQ366 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to members of the PDE2A sub-family, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE3A |
| Product Reference Code: | IQ365 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to PDE3A, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE3B |
| Product Reference Code: | IQ364 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to PDE3B sub-family, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE4A |
| Product Reference Code: | IQ363 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to members of the PDE4A sub-family, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE4B |
| Product Reference Code: | IQ362 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to members of the PDE4B sub-family, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE5A |
| Product Reference Code: | IQ360 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to the PDE5A isoform, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE7A |
| Product Reference Code: | IQ359 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to the PDE7A1 isoform, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Rabbit Anti-PDE9A |
| Product Reference Code: | IQ358 |
| Species Reactivity: | The antibody selectively detects proteins corresponding to the PDE9A isoform, in human, mouse rat ; |
| Applications: | IHC; IP; WB; |
| Primary Description: | Mouse Anti-PP2A B/PR55 alpha [2G9] |
| Product Reference Code: | IQ548 |
| Species Reactivity: | Human, mouse, rat (experimentally determined), porcine, rabbit, chicken, xenopus (not tested but identical antigenic sequence and thus predicted to be recognized); recognizes very well isoforms alpha and rat delta, weakly the human beta isoform, very weakly the rabbit gamma isoform |
| Applications: | WB, IP |