A germ cell is a cell that gives rise to the gametes that reproduces sexually. Gametes for example, sperm and eggs, conjoin to create a zygote which can create a fetus.
Within the gonads cell division matures into eggs or sperm produced as cells able to undergo meiosis and mitosis.
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Eme1 (Msm4) Antibody- Mouse Anti-Eme1 (Msm4)
EME1 complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein (MUS81) to form an endonuclease complex which cleaves branched DNA structures, especially those arising during stalled DNA replication. The protein may be involved in repairing DNA damage and in maintaining genomic stability. It interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. Alternative splicing results in multiple transcript variants.
£183.00
HCG beta Antibody- Mouse anti-HCG beta
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. The unique beta chain confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. hCG acts to maintain the corpus luteum until the developing placenta is able to produce the required levels of oestrogen and progesterone.
£226.00
hnRNP-A1 Antibody- Mouse Anti-hnRNP-A1
This protein belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm The hnRNP proteins have distinct nucleic acid binding properties hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm This protein along with other hnRNP proteins is exported from the nucleus probably bound to mRNA and is immediately re imported Its M9 domain acts as both a nuclear localization and nuclear export signal The encoded protein is involved in the packaging of pre mRNA into hnRNP particles transport of poly A mRNA from the nucleus to the cytoplasm and may modulate splice site selection It is also thought to have a primary role in the formation of specific myometrial protein species in parturition Multiple alternatively spliced transcript variants have been found for the hnRNP A1 gene but only two transcripts are fully described These variant have multiple alternative transcription initiation sites and multiple polyA sites
£226.00
hnRNP-A1 Antibody- Mouse Anti-hnRNP-A1
This protein belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm The hnRNP proteins have distinct nucleic acid binding properties hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm This protein along with other hnRNP proteins is exported from the nucleus probably bound to mRNA and is immediately re imported Its M9 domain acts as both a nuclear localization and nuclear export signal The encoded protein is involved in the packaging of pre mRNA into hnRNP particles transport of poly A mRNA from the nucleus to the cytoplasm and may modulate splice site selection It is also thought to have a primary role in the formation of specific myometrial protein species in parturition Multiple alternatively spliced transcript variants have been found for the hnRNP A1 gene but only two transcripts are fully described These variant have multiple alternative transcription initiation sites and multiple polyA sites
£226.00
hnRNP-A1 Antibody- Mouse Anti-hnRNP-A1
This protein belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm The hnRNP proteins have distinct nucleic acid binding properties hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm This protein along with other hnRNP proteins is exported from the nucleus probably bound to mRNA and is immediately re imported Its M9 domain acts as both a nuclear localization and nuclear export signal The encoded protein is involved in the packaging of pre mRNA into hnRNP particles transport of poly A mRNA from the nucleus to the cytoplasm and may modulate splice site selection It is also thought to have a primary role in the formation of specific myometrial protein species in parturition Multiple alternatively spliced transcript variants have been found for the hnRNP A1 gene but only two transcripts are fully described These variant have multiple alternative transcription initiation sites and multiple polyA sites
£183.00
hnRNP-A1 Antibody- Mouse Anti-hnRNP-A1
This protein belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm The hnRNP proteins have distinct nucleic acid binding properties hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm This protein along with other hnRNP proteins is exported from the nucleus probably bound to mRNA and is immediately re imported Its M9 domain acts as both a nuclear localization and nuclear export signal The encoded protein is involved in the packaging of pre mRNA into hnRNP particles transport of poly A mRNA from the nucleus to the cytoplasm and may modulate splice site selection It is also thought to have a primary role in the formation of specific myometrial protein species in parturition Multiple alternatively spliced transcript variants have been found for the hnRNP A1 gene but only two transcripts are fully described These variant have multiple alternative transcription initiation sites and multiple polyA sites
£183.00
PDE3A Antibody- Rabbit Anti- Phosphodiesterase 3A
Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3 5-monophosphate (cAMP and cGMP) Thus these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling The PDE3 enzyme belongs to a family of PDEs known as cGMP-inhibited PDEs The enzymes bind both cGMP and cAMP with different affinities The PDE3 family is comprised of two genes PDE3A and PDE3B
£226.00
PDE3B Antibody- Rabbit Anti--Phosphodiesterase 3B
Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3 5-monophosphate (cAMP and cGMP) Thus these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling The PDE3 enzyme belongs to a family of PDEs known as cGMP-inhibited PDEs The enzymes bind both cGMP and cAMP with different affinities The PDE3 family is comprised of two genes PDE3A and PDE3B
£226.00
PDE7A Antibody- Rabbit Anti-phosphodiesterase 7A
Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3 5-monophosphate (cAMP and cGMP) Thus these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling The PDE7 enzyme belongs to a family of cAMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger cAMP Two genes (PDE7A and PDE7B) encode the PDE7 family each with multiple splice variants
£226.00
Progesterone Receptor C262 Antibody- Mouse Anti- Progesterone Receptor C262
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£183.00
Progesterone Receptor C262 Antibody- Mouse Anti- Progesterone Receptor C262
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£226.00
Progesterone Receptor N559 Antibody- Mouse Anti- Progesterone Receptor N559
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£183.00
Progesterone Receptor N559 Antibody- Mouse Anti- Progesterone Receptor N559
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£226.00
