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HIV-2 Nef Antibody- Rat Anti-HIV-2 Nef
Nef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2 It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors Thereby it enhances viral infectivity and affects T-cell signalling
£226.00
HIV1 integrase Antibody- Mouse Anti-HIV1 integrase
Integrase is an enzyme, a product of the HIV1 Gag/Pol gene; the other two enzymes being reverse transcriptase and protease. The human immunodeficiency virus (HIV-1) uses an enzyme, a so-called integrase, to carry out the integration of its viral DNA into the host chromosome thereby tricking the host cell machinery into making viral proteins. The HIV-1 integrase is a protein of 32 kDa and is composed of three domains. No cellular homologue of HIV integrase has been described, so potential inhibitors to this enzyme could be relatively nontoxic.
£226.00
HIV1 P17 Gag Antibody- Mouse Anti-HIV1 P17 Gag
HIV1 p17 is the matrix protein of the Gag polyprotein which performs highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA
£226.00
