The Calcium ion is very important for human cellular processes.
In its Ca2+ structure, the movement of the ion inbound and out bound of the cell cytoplasm is an important part of cell signalling and signal transduction. It has important regulation roles in neurotransmission and extracellular processes like muscle contraction.
Many enzymes require the Calcuim Ion as cofactor and calcium is important in bone formation.
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Nidogen/Enactin-G1 Domain Antibody- Rat Anti-Nidogen/Enactin-G1 Domain
Nidogen 1 / Entactin is a sulfated glycoprotein which is widely distributed in basement membranes and that is tightly associated with laminin Also binds to collagen IV It probably has a role in cell extracellular matrix interactions
£226.00
Nidogen/Enactin-G1 Domain Antibody- Rat Anti-Nidogen/Enactin-G1 Domain
Nidogen 1 / Entactin is a sulfated glycoprotein which is widely distributed in basement membranes and that is tightly associated with laminin Also binds to collagen IV It probably has a role in cell extracellular matrix interactions
£183.00
Nidogen/Enactin-G2 Domain Antibody- Rat Anti-Nidogen/Enactin-G2 Domain
Nidogen 1 / Entactin is a sulfated glycoprotein which is widely distributed in basement membranes and that is tightly associated with laminin Also binds to collagen IV It probably has a role in cell extracellular matrix interactions
£226.00
Nidogen/Enactin-G3 Domain Antibody- Rat Anti-Nidogen/Enactin-G3 Domain
Nidogen 1 / Entactin is a sulfated glycoprotein which is widely distributed in basement membranes and that is tightly associated with laminin Also binds to collagen IV It probably has a role in cell extracellular matrix interactions
£226.00
Nidogen/Enactin-G3 Domain Antibody- Rat Anti-Nidogen/Enactin-G3 Domain
Nidogen 1 / Entactin is a sulfated glycoprotein which is widely distributed in basement membranes and that is tightly associated with laminin Also binds to collagen IV It probably has a role in cell extracellular matrix interactions
£183.00
Progesterone Receptor C262 Antibody- Mouse Anti- Progesterone Receptor C262
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£183.00
Progesterone Receptor C262 Antibody- Mouse Anti- Progesterone Receptor C262
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£226.00
Progesterone Receptor N559 Antibody- Mouse Anti- Progesterone Receptor N559
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£183.00
Progesterone Receptor N559 Antibody- Mouse Anti- Progesterone Receptor N559
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£226.00
Trichohyalin granules (THG) AE15 Antibody- Mouse Anti-trichohyalin granules (THG) AE15
Trichohyalin is a hair follicle protein with characteristics similar to those of profilaggrin (135940) involucrin (147360) and loricrin (152445) Trichohyalin is incorporated into the IF (intermediate filament)-like structures in the mature cells of the hair follicles inner root sheath Like profilaggrin involucrin and loricrin trichohyalin becomes highly crosslinked by the enzyme transglutaminase The trichohyalin molecule has a mass of approximately 200 kD and consists predominantly of tandem repeats of an approximately 23-amino acid sequence Fietz et al (1992) used a sheep trichohyalin cDNA probe in tritium-labeled in situ hybridization to demonstrate that the human THL gene is located in the region 1q211-q23 probably 1q213 Profilaggrin involucrin and loricrin map to the same area suggesting that the 4 proteins form a novel superfamily of epithelial structural proteins By analysis of human-rodent somatic cell hybrids and fluorescence in situ hybridization Lee et al (1993) confirmed the mapping of THL to 1q21
£183.00
