Metal ions are common cofactors or helper factors (a non-protein substance that is bound to protein) and is an essential requirement to enable that protein to work. Often these cofactors work with enzymes.
Common inorganic metal ion cofactors include iron, magnesium, copper and zinc. Sometimes an inorganic and organic metal ion combines to enable effective functioning. For example in blood, the haem proteins consist of iron complemented by an organic compound porphyrins.
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PDE4D Antibody- Rabbit Anti- Phosphodiesterase 4D
Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3 5-monophosphate (cAMP and cGMP) Thus these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling The PDE5 enzyme belongs to a family of cGMP-dependent PDEs that provide the major means of inactivating the key intracellular second messenger cGMP
£226.00
Progesterone Receptor Antibody- Phospho (Ser162) - Mouse Anti-Progesterone Receptor - Phospho (Ser162)
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy Progesterone receptor a member of the steroid receptor superfamily mediates the physiologic effects of progesterone The PGR gene uses separate promoters and translational start sites to produce 2 isoforms PRA and PRB which are identical except for an additional 165 amino acids present only in the N terminus of PRB Although PRA and PRB share several structural domains they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap
£226.00
