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Nuclear Signalling Nuclear Import/Export

Importins and exportins are group of proteins called karyopherins which are responsible for transporting molecules and other proteins from the cytoplasm to the cell nucleus. The process is normally facilitated via ingress and egress via nuclear pores which are distributed around the nuclear envelope.

Powered by the energy releasing Ran gradient, Importins bind to their molecular load, pass through the nuclear pore complexes and integrate with Ran-GTP to drop there load.

Exportins essentially reverse the process, within the nucleus the exportin binds to its cargo and exits via the nuclear pore complex to disassociate when the cargo movement is complete.

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Primary Description:

Mouse Anti-hnRNP K [3C2] - ChIP Grade

Product Reference Code: IQ213
Species Reactivity:

Mouse, Rat, Hamster, Cow, Human, Xenopus laevis

Applications:

WB, IP, ELISA, ICC/IF, Flow Cyt, ChIP/Chip, IHC (rat)

£226.00

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Immunoprecipitation - Drosophila FMR1 antibody [6A15] using tissue lysate from Drosophila cellularizing embryos
Primary Description:

Mouse Anti-Drosophila FMR1 [6A15]

Product Reference Code: IQ219
Species Reactivity:

Fruit fly (Drosophila melanogaster)

Does not react with

Human

Applications:

IP, ICC/IF, ELISA, WB

£226.00

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Immunoprecipitation - Drosophila FMR1 antibody [6A15] using tissue lysate from Drosophila cellularizing embryos were
Primary Description:

Mouse Anti-Drosophila FMR1 [6A15]

Product Reference Code: IQ274
Species Reactivity:

Fruit fly (Drosophila melanogaster)

Does not react with

Human

Applications:

IP, ICC/IF, ELISA, WB

£183.00

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Immunocytochemistry/ Immunofluorescence - Anti-Emerin antibody at a 1/100 dilution
Primary Description:

Goat Anti-Emerin 

Product Reference Code: IQ323
Species Reactivity:

Mouse, Rat, Hamster, Human

Applications:

WB, ICC/IF

£226.00

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Immunocytochemistry/ Immunofluorescence - Anti-Emerin antibody at a 1/100 dilution
Primary Description:

Sheep Anti-Emerin 

Product Reference Code: IQ324
Species Reactivity:

Mouse, Rat, Hamster

Applications:

WB, ICC/IF, Electron Microscopy

£226.00

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Immunocytochemistry/ Immunofluorescence - GP210 antibody on formaldehyde fixed HeLa cells
Primary Description:

Rabbit Anti-gp210 

Product Reference Code: IQ244
Species Reactivity:

Human, Rat, Xenopus laevis. Predicted to work with all Mammals

Applications:

WB, ICC/IF

£226.00

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Methanol/acetone fixed HeLa cells stained with rabbit anti gp210
Primary Description:

Rabbit Anti-gp210 

Product Reference Code: IQ294
Species Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC/IF, WB

£226.00

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Western blot using Anti-hnRNP A1, clone 4B10 on Hela cell lysate
Primary Description:

Mouse Anti-hnRNP A1 [4B10]

Product Reference Code: IQ205
Species Reactivity:

Human, Mouse (IP WB) 

Applications:

ELISA, ICC/IF, IP, WB

£226.00

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Western blot using Anti-hnRNP A1, clone 4B10 on Hela cell lysate
Primary Description:

Mouse Anti-hnRNP A1 [4B10]

Product Reference Code: IQ262
Species Reactivity:

Human, Mouse (IP WB)

Applications:

ELISA, ICC/IF, IP, WB

£183.00

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-hnRNP A1 antibody [9H10] staining human lung. Staining is localized to the nucleus.
Primary Description:

Mouse Anti-hnRNP A1 [9H10]

Product Reference Code: IQ206
Species Reactivity:

Mouse, Human

Applications:

Flow Cyt, IHC-P, ELISA, WB, IP, ICC/IF

£226.00

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-hnRNP A1 antibody [9H10] staining human lung. Staining is localized to the nucleus.
Primary Description:

Mouse Anti-hnRNP A1 [9H10]

Product Reference Code: IQ263
Species Reactivity:

Mouse, Human

Applications:

Flow Cyt, IHC-P, ELISA, WB, IP, ICC/IF

£183.00

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Primary Description:

Mouse Anti-hnRNP K [3C2] - ChIP Grade

Product Reference Code: IQ269
Species Reactivity:

Mouse, Rat, Hamster, Cow, Human, Xenopus laevis

Applications:

WB, IP, ELISA, ICC/IF, Flow Cyt, ChIP/Chip, IHC (Rat)

£183.00

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Primary Description:

Rat Anti-KPNA2 [2G7]

Product Reference Code: IQ305
Species Reactivity:

Mouse, Human. Predicted to work with Rat 

Applications:

WB

£226.00

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Western blot - Ran antibody at a 1/500 dilution staining approximately 26kDa Ran in Xenopus egg extract (lane X, 50µg per lane) and HeLa total cell extract (lane Hu, 50µg per lane)
Primary Description:

Rabbit Anti-Ran

Product Reference Code: IQ245
Species Reactivity:

Human, Xenopus laevis

Applications:

IHC-P, ICC/IF, IP, WB

£183.00

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Immunohistochemistry showing RanGAP on formalin fixed paraffin embedded skin tissue at 1:100
Primary Description:

Rabbit Anti-RanGAP1

Product Reference Code: IQ246
Species Reactivity:

Mouse, Human, Xenopus laevis

Applications:

IHC-P, ICC/IF, WB

£183.00

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Immunohistochemistry of RCC1 on formalin fixed paraffin embedded skin tissue at 1:100
Primary Description:

Rabbit Anti-RCC1

Product Reference Code: IQ247
Species Reactivity:

Human, Xenopus laevis

Applications:

IHC-P, IP, ICC/IF, WB

£183.00

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