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Nuclear Transport Antibodies

Nuclear transport antibodies relate to the large molecules are carried bi-directionally across the nuclear envelope by a RAN (ras-related nuclear protein) GTP nuclear transport cycle.

Nuclear transport processes RNA and proteins are enabled to enter the nucleus via specialist karyopherin proteins importins and facilitated outbound by exportins via the nuclear pore structures e.g. Transportin1 . Both exportins and importins abilities are regulated by GTPase.

Nuclear transport antibodies are useful in understanding the direction of the nuclear transport cycle is triggered by localisation signals in an active process that can be negatively affected in human neurodegenerative diseases like Parkinsons and suggest nuclear protein import directly participate in the pathogenesis of diseases such as hypertension, atherosclerosis, cancer, viral infection, and diabetes.

Nuclear transport antibodies are available in the following various quantities including 0.05 ml, 0.1ml, 0.2 ml, 1 ml

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Immunocytochemistry/ Immunofluorescence - Anti-Emerin antibody at a 1/100 dilution
Primary Description:

Sheep Anti-Emerin 

Product Reference Code: IQ324
Species Reactivity:

Mouse, Rat, Hamster

Applications:

WB, ICC/IF, Electron Microscopy

£226.00

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Primary Description:

Rat Anti-KPNA2 [2G7]

Product Reference Code: IQ305
Species Reactivity:

Mouse, Human. Predicted to work with Rat 

Applications:

WB

£226.00

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Primary Description:

Rabbit Anti-Ran

Product Reference Code: IQ245
Species Reactivity:

Reacts with human Xenopus Ran protein ;

Applications:

IF; IP; WB;

£183.00

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Immunohistochemistry of RanGAP on formalin fixed paraffin embedded skin tissue
Primary Description:

Rabbit Anti-RanGAP

Product Reference Code: IQ173
Species Reactivity:

Reacts with human Xenopus RanGAP ;

Applications:

IF; WB; IHC(P)

£226.00

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Immunohistochemistry showing RanGAP on formalin fixed paraffin embedded skin tissue at 1:100
Primary Description:

Rabbit Anti-RanGAP

Product Reference Code: IQ246
Species Reactivity:

Reacts with human Xenopus RanGAP ;

Applications:

IF; WB; IHC(P)

£183.00

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Immunohistochemistry of RanGEF (RCC1) on formalin fixed paraffin embedded skin tissue at 1:100
Primary Description:

Rabbit Anti-RanGEF (RCC1)

Product Reference Code: IQ247
Species Reactivity:

Reacts with human Xenopus RanGEF ;

Applications:

IF; IP; WB; IHC(P)

£183.00

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Primary Description:

Mouse Anti-TAP [53H8]

Product Reference Code: IQ224
Species Reactivity:

Human TAP. Detects a band of approximately 68 kDa ;

Applications:

E; IF; IP; WB;

£226.00

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Primary Description:

Mouse Anti-Transportin1 [D45]

Product Reference Code: IQ223
Species Reactivity:

Human transportin1. Detects a band of approximately 90 kDa. Cross reacts with monkey rabbit ;

Applications:

E; IF; IP; WB;

£226.00

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