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Nuclear Transport Antibodies

Nuclear transport antibodies relate to the large molecules are carried bi-directionally across the nuclear envelope by a RAN (ras-related nuclear protein) GTP nuclear transport cycle.

Nuclear transport processes RNA and proteins are enabled to enter the nucleus via specialist karyopherin proteins importins and facilitated outbound by exportins via the nuclear pore structures e.g. Transportin1 . Both exportins and importins abilities are regulated by GTPase.

Nuclear transport antibodies are useful in understanding the direction of the nuclear transport cycle is triggered by localisation signals in an active process that can be negatively affected in human neurodegenerative diseases like Parkinsons and suggest nuclear protein import directly participate in the pathogenesis of diseases such as hypertension, atherosclerosis, cancer, viral infection, and diabetes.

Nuclear transport antibodies are available in the following various quantities including 0.05 ml, 0.1ml, 0.2 ml, 1 ml

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Immunocytochemistry/ Immunofluorescence - Anti-Emerin antibody at a 1/100 dilution
Primary Description:

Sheep Anti-Emerin 

Product Reference Code: IQ324
Species Reactivity:

Mouse, Rat, Hamster

Applications:

WB, ICC/IF, Electron Microscopy

£226.00

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Primary Description:

Rat Anti-KPNA2 [2G7]

Product Reference Code: IQ305
Species Reactivity:

Mouse, Human. Predicted to work with Rat 

Applications:

WB

£226.00

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IHC using Lamin A+C Antibody [JOL2] on fixed human colon
Primary Description:

Mouse Anti-Lamin A+C [JOL2]

Product Reference Code: IQ608
Species Reactivity:

Human, African Green Monkey

Applications:

IP, WB, IHC (P)

£249.00

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IHC using Lamin A+C Antibody [JOL2]: HRP conjugate on fixed human colon
Primary Description:

Mouse Anti-Lamin A+C [JOL2]: Horseradish peroxidase (HRP)

Product Reference Code: IQ608HRP
Species Reactivity:

Human, African Green Monkey

Applications:

IP, WB, IHC (P)

£245.00

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Western blot - Ran antibody at a 1/500 dilution staining approximately 26kDa Ran in Xenopus egg extract (lane X, 50µg per lane) and HeLa total cell extract (lane Hu, 50µg per lane)
Primary Description:

Rabbit Anti-Ran

Product Reference Code: IQ245
Species Reactivity:

Human, Xenopus laevis

Applications:

IHC-P, ICC/IF, IP, WB

£183.00

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Immunohistochemistry showing RanGAP on formalin fixed paraffin embedded skin tissue at 1:100
Primary Description:

Rabbit Anti-RanGAP1

Product Reference Code: IQ246
Species Reactivity:

Mouse, Human, Xenopus laevis

Applications:

IHC-P, ICC/IF, WB

£183.00

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Immunohistochemistry of RCC1 on formalin fixed paraffin embedded skin tissue at 1:100
Primary Description:

Rabbit Anti-RCC1

Product Reference Code: IQ247
Species Reactivity:

Human, Xenopus laevis

Applications:

IHC-P, IP, ICC/IF, WB

£183.00

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Western blot - TAP1 antibody [53H8]
Primary Description:

Mouse Anti-TAP1 [53H8]

Product Reference Code: IQ224
Species Reactivity:

Human 

Applications:

ELISA, WB, IP, ICC/IF

£226.00

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Transportin 1 antibody [D45]
Primary Description:

Mouse Anti-Transportin 1 [D45]

Product Reference Code: IQ223
Species Reactivity:

Mouse, Rabbit, Human, Monkey

Applications:

Flow Cyt, ICC/IF, IHC-P, ELISA, WB, IP

£226.00

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