The Golgi Apparatus is an cellular organelle responsible for processing and packaging proteins post synthesis and for preparing the protein for forwarding to its destination.
Present in most organisms cells it is composed of cisternae or sac like structures in membrane layers arranged in stacks with a typical cell containing 40 to 100 stacks. As the protein is progressed through the stacks, Golgi specific enzymes are able modify the protein through glygosylation and phosphorylation thus enabling a shaper targeting of the right protein to the right destination.
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3D1.1 Antibody (Parathyroid hormone like protein) - Mouse Anti PTHLH
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone
£226.00
Parathyroid Hormone Antibody - Mouse Anti-Parathyroid Hormone (PTH)
The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH)
£226.00
