The nuclear envelope is a thin membrane that surrounds the genetic material in eukaryotic cells. It consists of a double layer of lipids, separating the nucleus content, principally DNA, from the surrounding cell cytoplasm.
The outer part of the nuclear envelope membrane is rough endoplasmic reticulum spotted as it is with ribosomes. The inner part consists of flat membrane proteins e.g. Emerin which are linked to the nuclear lamina and mutations in Lamins A and B.
The nuclear envelope is perforated with pores which enable the transport of proteins and RNA between the nucleus and cytoplasm. The inner and outer membranes conjoin at each nuclear pore site.
Nuclear envelope diseases or envelopathies implicated include muscular dystrophy and diabetes.
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| Primary Description: | Goat Anti-Emerin |
| Product Reference Code: | IQ323 |
| Species Reactivity: | Mouse, Rat, Hamster, Human |
| Applications: | WB, ICC/IF |
| Primary Description: | Sheep Anti-Emerin |
| Product Reference Code: | IQ324 |
| Species Reactivity: | Mouse, Rat, Hamster |
| Applications: | WB, ICC/IF, Electron Microscopy |
| Primary Description: | Rabbit Anti-gp210 |
| Product Reference Code: | IQ244 |
| Species Reactivity: | Human, Rat, Xenopus laevis. Predicted to work with all Mammals |
| Applications: | WB, ICC/IF |
| Primary Description: | Rabbit Anti-gp210 |
| Product Reference Code: | IQ294 |
| Species Reactivity: | Mouse, Rat, Human, Monkey |
| Applications: | ICC/IF, WB |
| Primary Description: | Mouse Anti-Lamin A + C antibody [JoL5] - Nuclear Envelope Marker |
| Product Reference Code: | IQ188 |
| Species Reactivity: | Mouse, Human |
| Applications: | ICC/IF, WB |
![Lamin A + C antibody [JoL5] - Nuclear Envelope Marker](/images/products/thumbnails/1296122004-63796900.jpg)
| Primary Description: | Mouse Anti-Lamin A + C antibody [JoL5] - Nuclear Envelope Marker |
| Product Reference Code: | IQ252 |
| Species Reactivity: | Mouse, Human |
| Applications: | ICC/IF, WB |
![Lamin A + C antibody [JoL5] - Nuclear Envelope Marker](/images/products/thumbnails/1296122039-84472900.jpg)
| Primary Description: | Mouse Anti-Lamin A [JOL4] |
| Product Reference Code: | IQ330 |
| Species Reactivity: | Human, Mouse |
| Applications: | IF, IHC(Fr), IP, WB |
![Lamin A Antibody [JOL4]](/images/products/thumbnails/1360077006-57384400.jpg)
| Primary Description: | Mouse Anti-Lamin A+C [JOL2] |
| Product Reference Code: | IQ332 |
| Species Reactivity: | Human, African Green Monkey |
| Applications: | ICC/IF, IHC-Fr, IHC-P, WB, IP, Flow Cyt |
![Lamin A+C Antibody [JOL2]](/images/products/thumbnails/1301319085-80086100.jpg)
| Primary Description: | Mouse Anti-Lamin A + C antibody [JoL3] - Nuclear Envelope Marker |
| Product Reference Code: | IQ251 |
| Species Reactivity: | Mouse, Rat, Human |
| Applications: | WB, ICC/IF |
![Lamin A+C Antibody [JoL3] - Nuclear Envelope Marker](/images/products/thumbnails/1296122038-23832100.jpg)
| Primary Description: | Mouse Anti-Lamin A+C mutant R482W [5H8-B4] |
| Product Reference Code: | IQ546 |
| Species Reactivity: | Human |
| Applications: | WB, IP, ICC/IF |
![Lamin A+C mutant R482W Antibody [5H8-B4]](/images/products/thumbnails/1317729851-56653800.jpg)
| Primary Description: | Mouse Anti-Lamin A+C mutant R482W [5H8-B4]: Horseradish Peroxidase (HRP) |
| Product Reference Code: | IQ546HRP |
| Species Reactivity: | Human |
| Applications: | IP, WB |
| Primary Description: | Mouse Anti-Lamin A/C [JOL3]: FITC |
| Product Reference Code: | IQ656FITC |
| Species Reactivity: | Human, Mouse, Rat |
| Applications: | ICC/IF |
![Lamin A/C antibody [JOL3]: FITC](/images/products/thumbnails/1474542886-93339500.jpg)
| Primary Description: | Mouse Anti-Lamin B1 + B2 antibody [X223] - Nuclear Envelope Marker |
| Product Reference Code: | IQ176 |
| Species Reactivity: | Mouse, Rat, Cow, Human |
| Applications: | ICC/IF, WB |
![Lamin B1 + B2 antibody [X223] - Nuclear Envelope Marker](/images/products/thumbnails/1367494501-71569900.jpg)
| Primary Description: | Rabbit Anti-Lamin C |
| Product Reference Code: | IQ177 |
| Species Reactivity: | Human, Mouse, Rat |
| Applications: | ICC/IF, IHC-P, IHC-Fr, WB, Flow |
| Primary Description: | Rabbit Anti-Nesprin 1 |
| Product Reference Code: | IQ171 |
| Species Reactivity: | Mouse, Human |
| Applications: | IHC (PFA fixed), WB, ICC/IF, IHC-Fr |
| Primary Description: | Mouse Anti-Nesprin 2 [K20-478-5] |
| Product Reference Code: | IQ562 |
| Species Reactivity: | Human |
| Applications: | ICC/IF, WB, IP, Electron microscopy |
![Nesprin 2 Antibody [K20-478-5]](/images/products/thumbnails/1327498550-33070600.jpg)
