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Transcription Factor Antibodies

Transcription factor antibodies are useful in exploring the role of key proteins that regulate, via RNA inhibition or activation, the transcription from DNA to mRNA.

Associated with mutagenic diseases various transaction factor antibodies protein research area linked to human cancer and syndromes e.g Rett syndrome

Transcription factor antibodies are available in the following volumes including 0.05 ml, 0.1 ml, 0.2 ml, 1 ml and 2 ml.

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EAPP (E2F- associated phosphoprotein) Antibody ; Mouse Anti-EAPP (E2F- associated phosphoprotein)
Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis
£226.00

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Mus81 Antibody- Mouse Anti-Mus81
Reduction or loss of a protein called Mus81 can led to the development of lymphomas and other tumours in mice Mus81 is a protein long thought to be involved in repairing DNA that is damaged during normal metabolic processes
£183.00

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